Lions 49ers 2025 Calendar. The nfl on thursday released a handful of key dates for the 2025 season. The san francisco 49ers’ regular season began on september 9, 2024, and will end on january 5, 2025.
Nfl media’s tom pelissero provided the dates which were distributed to teams in a memo issued. The san francisco 49ers will receive a slight reprieve in the 2025 season thanks to their abysmal 2024 campaign.